A novel calcineurin splice variant that modifies calcineurin activity
نویسندگان
چکیده
منابع مشابه
Calcineurin selectively docks with the dynamin Ixb splice variant to regulate activity-dependent bulk endocytosis.
Depolarization of nerve terminals stimulates rapid dephosphorylation of two isoforms of dynamin I (dynI), mediated by the calcium-dependent phosphatase calcineurin (CaN). Dephosphorylation at the major phosphorylation sites Ser-774/778 promotes a dynI-syndapin I interaction for a specific mode of synaptic vesicle endocytosis called activity-dependent bulk endocytosis (ADBE). DynI has two main s...
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What do you think about the state of research in France? I am rather concerned. France has the financial and human resources to carry on highly competitive research, yet it needs a major overhaul of its current system. I would like to convince the Government to invest much more and for a longer time in basic science — applied research won’t be effective if not supported by strong academic resea...
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ژورنال
عنوان ژورنال: European Journal of Biochemistry
سال: 2001
ISSN: 0014-2956
DOI: 10.1046/j.0014-2956.2001.02551.x